Our automated review system seeks to locate the PIC elements of PICO. We didn’t have the resource to do the ‘O’ (outcomes) which seems a shame. But we want to explore incorporating it and an important starting block is having a list of outcomes. Such a list doesn’t – obviously – exist. I put an email request to the EBHC maillist and got a number of responses that have started me down the route of attempting to compile a list that might prove useful to me and others.
Another option to explore is scraping the outcomes listed in ct.gov, a fairly straightforward task but the outcomes aren’t ‘clean’. By that, if you look at these example outcomes from the site they’re quite long, which can be problematic!
- Measure Metformin Induced effects in phosphorylation of S6K, 4E-BP-1 and AMPK via immunohistochemical analysis
- Antibody response rate to measles at 6 weeks postvaccination
- Change in Maximum Forced Expiratory Volume at One Second (FEV1)
- Biomarkers will be identified to help predict future prostate cancer risks and patients likely to benefit from preventive strategies
A further option is the COMET Initiative (Core Outcome Measures in Effectiveness Trials) and I’ve reached out to them for help.
So, very much a work in progress! As I type/write this we have just one list but we are hopeful that we’ve located two other lists, one in CVD and one in schizophrenia.
List to date:
From the SONG Initiative (Standardised Outcomes in Nephrology)
ability to travel
ability to work
drop in blood pressure
impact on friends
impact on family
washed out after dialysis