Trip Database Blog

I’ve just uploaded the latest batch of manually curated records, a total of 613 new articles. This number is small, relative to the larger number we automatically grab, but it typically represents the content at the top of the evidence pyramid.

Each month hundreds of sites are visited to explore if they have published any new evidence, if they have this is placed in a spreadsheet before uploading to the site. We record the following bits of data for each record:

• Publication
• Title
• URL
• Year

When we have finished the monthly collection we upload it to our system and that does the rest. New content is typically available by the next day and often much sooner.

Below is a small sample of the records added this month:

1. Opioid Treatments for Chronic Pain (AHRQ)
2. Acute Lymphoblastic Leukemia in Adults (Cancer Care Alberta)
3. Systematic review of needs for medical devices for ageing populations (WHO)
4. Addressing Social Determinants of Health and Mitigating Health Disparities Across the Lifespan in Congenital Heart Disease (American Heart Association)
5. Remote monitoring of patients with COVID-19 (KCE – Belgian Health Care Knowledge Centre)
6. Pacritinib (Vonjo) – To treat intermediate or high-risk primary or secondary myelofibrosis in adults with low platelets (FDA)
7. Factors associated with outbreaks of SARS-CoV-2 in nursing homes (HIQA, Ireland)
8. Paediatric Intensive Care Nutrition (James Lind Alliance Priority Setting Partnerships)
9. Gout: diagnosis and management (NICE guideline)
10. Digital smartphone intervention to recognise and manage early warning signs in schizophrenia to prevent relapse: the EMPOWER feasibility cluster RCT (NIHR HTA)
11. Peanut allergy: peanut-avoidant diet and access to adrenaline injector pens (Prescrire)
12. Lipoedema – diagnosis, treatment, and experiences (SBU)
13. Impaired Visual Acuity in Older Adults: Screening (US Preventive Services)
14. Monkeypox: diagnostic testing (UK Health Security Agency)
15. Regulation and financing of prenatal screening and diagnostic examinations for fetal anomalies in selected European countries (Austrian Institute for Health Technology Assessment)

The evidence above is a joy to see and represents a small fraction of the total uploaded each and every month.

Having great content is a key element of Trip’s continued success, that’s why we spend so much resource on it!

In 2014 I wrote this:

“We have a manual system for handling synonyms in our search. This means that if someone searches for IBS we automatically search for irritable bowel syndrome. I’m currently undertaking a review of these synonyms, a long-winded and problematic process – but well worth doing.“

When I say/said a manual list we started the synonyms in Trip by exploring the top used search terms in Trip (I think it was the top 8-10,000 terms) and manually looking through them to see if any might have synonyms. So, when I came across IBS in the list, I would add irritable bowel syndrome. When a user searched on Trip for IBS we would effectively insert the other term, making it IBS OR irritable bowel syndrome. This is a crude but surprisingly effective system and – with the new back-end work finally coming to the end, it’s time to review them again.

This is what I’m looking at:

This might take a while 🙂

Learning lessons from Covid-19, Trip has started actively adding higher-quality content related to Monkeypox. Trip users are actively searching for information and the information ‘landscape’ is changing rapidly. As such, Trip is accelerating it’s content ‘acquisition’.

A search for monkeypox on Trip currently has these results in the top 5:

If you know of any great resources, please let Trip know via monkeypox@tripdatabase.com.

Ariadne Labs is a joint center for health systems innovation at Brigham and Women’s Hospital and the Harvard T.H. Chan School of Public Health. They approached Trip earlier in the year to take part in their Better Evidence initiative and this has resulted in Trip Pro being made available, for free, in 20 schools across 12 countries in Africa.

In little over 24 hours we’ve made some significant changes to the combat injuries filter. We’ve increased the yield of higher-quality articles from 2,000 to nearly 4,000. In conversation with people it’s become apparent that simply pointing to a large number of results isn’t great – as it suggests the user will have to browse the articles. In actual fact, they are more likely to have a clinical question.

So, we’re going to try to create an evidence table, pre-loaded with possible questions. As with the previous post, this table should be added to as and when people reach out. If you have suggestions, please send them to jon.brassey@tripdatabase.com. And, to be clear, we’re not experts in this domain, hence being very open to help.

Topic	Combat setting (higher-quality evidence)	Combat setting (all evidence)	Any setting (higher-quality evidence)	Any setting (all evidence)
Amputation	121 results	965 results	1,613 results	13,515 results
Antibiotics	504 results	4,100 results	11,793 results	148,176 results
Anxiety	702 results	2,628 results	12,273 results	87,007 results
Bullet wounds	65 results	522 results	65 results	522 results
Burns	572 results	2,719 results	4,005 results	28,571 results
Compartment syndrome	174 results	963 results	947 results	14,125 results
First aid	93 results	266 results	402 results	1,752 results
PTSD	611 results	2,979 results	3,123 results	17,085 results
Tranexamic acid	42 results	111 results	696 results	3,226 results
Venous thromboembolism	164 results	464 results	3,192 results	14,389 results

Thanks to Tom for highlighting refugee health. The following do not have any combat setting filter, they’re just total topic results:

Topic	Higher-quality evidence	All evidence
PTSD refugees	207 results	565 results
Refugee health	648 results	2,782 results
Refugee mental health	455 results	1,292 results
Unaccompanied minor refugees	36 results	92 results

Kate has highlighted the wonderful Evidence Aid. They have a number of pertinent evidence collections, including Health of refugees and asylum seekers.

Again, any suggestions via jon.brassey@tripdatabase.com

Earlier today I heard on the radio about two British surgeons running online training on military surgical techniques for surgeons/doctors in Ukraine. As Trip is a global repository of some of the best evidence available we thought it might be beneficial to try to bring together some of the best ‘combat’ evidence. To that end we have started work on a search filter. This is our starting list:

• (shrapnel AND (wound OR injury))
• military
• soldier
• (post-traumatic stress disorder AND (soldier or military))
• (bomb AND injuries)
• (bullet AND (wound OR injury))
• (bomb AND (wound OR injury))

These translates to this search string, which is 20,000 results. If you restrict to ‘evidence based’ content (this search string) it drops to a more manageable 2,000 results. However, this is still too many so it possibly requires more filtering. For instance:

• The above search but adding in surgery give nearly 5,800 results, or 732 results if you restrict to higher quality results
• Just looking at shrapnel injuries -(shrapnel AND (wound OR injury)) – gives 485 results or 16 results for the higher quality results.

Can you help us improve our offering? I guess this comes in two parts (1) improve the filter to locate more military-related articles, and (2) suggestions for pre-formulated searches (such as the surgery or shrapnel searches above)

Any suggestions please send them to jon.brassey@tripdatabase.com

UPDATE (15:26 on 06/03/2022)

Thanks to Becky I’ve added some additional terms:

• “armed forces”
• warfare
• army
• navy
• airforce

This finds extra articles, unfiltered it’s now just over 28,000 results, and just over 2,600 higher quality articles.

UPDATE (11:52 on 07/03/2022)

Thanks to Lina we’ve identified a number of new terms:

• gunshot
• firearm
• blast
• explosion

This now gives just over 44,000 results, and just over 3,500 for higher-quality content.

Update (14:01 on 07/03/2022)

Thank you to Igor and Tracy we’ve identified some other useful terms:

• shelling
• grenade
• “land mine”
• landmine
• artillery

This now gives just over 50,000 total results with nearly 4,000 higher-quality results.

We’ve just been contacted by a doctor undertaking a systematic review and he asked, for writing up the search strategy, how far back do our records go. Unfortunately it is not possible to give a definitive answer!

In part this relates to the recent post Journal coverage in Trip where we highlight the nature of incorporating documents. We typically say that the bulk of our content is from the year 2000 onwards. However, as we grab all the RCTs and systematic reviews in PubMed, those are our earliest records. So, we’ve got some systematic reviews and and RCTs from the 1950s (although the definition of these research types may well have changed since then) and our earliest guideline appears to be from the late 1990s!.

Trip is only as good as the content it searches, and as such, we are constantly exploring new sources of evidence to add. We are supported in this by our users who often contact us to alert us to content we don’t already include and we typically add new sources every month. This month has been particularly productive with 5 new publications. Four of these  (the Health Technology Assessments) were highlighted by a senior HTA investigator. The new sources are:

• Adelaide Health Technology Assessment
• AETSA HTA (Spain)
• Government of Alberta HTA
• Council for Choices in Health Care HTA (Finland)
• American Diabetes Association – guidelines

If you know of a source you think would be useful for Trip and it’s users then please get in touch sources@tripdatabase.com.

We regularly post blog articles highlighting a particular aspect of Trip. As these grow, having them in one place makes sense, so here we go!

Obtaining an overview of Trip

Getting the most from Trip – highlighting two videos that give users – both new and experienced – to get better results from Trip

Subscribing to Trip

The difference between free and Pro Trip

Institutional subscriptions – the costs involved in obtaining institutional access

Features

Understanding the full-text icons on Trip

Advanced search tip

Deleting ‘Recent’ search activity

Pyramids are back

Using Trip via mobiles or tablets

Content

Adding new content to Trip

Journal coverage in Trip

Years covered by Trip

Sources searched by Trip – a bit dated with some content no longer available and other content added, but it still gives a good account of what we cover.

This blog will expand over time as relevant articles are added. If you’d like to suggest new topics to cover then please let us know via jon.brassey@tripdatabase.com